28 : Systems Made Simple Inc.
| Location: | Syracuse, N.Y. |
| Annual growth rate: | 104.25% |
| 2009 revenue: | $33,805,880.00 |
| 2008 revenue: | $17,171,462.00 |
| 2007 revenue: | $3,875,893.00 |
| 2006 revenue: | $5,793,920.00 |
| 2005 revenue: | $1,942,353.00 |
| Leadership: | Ronald Fishbeck, CEO |
| Web site: | http://www.systemsmadesimple.com |